Jake Zimmerman

Photo of Jake
Jake Zimmerman
Professor of Chemistry
Meyer Hall of Science 271
525 South Main Street, Ada, OH, 45810
Research Interests
Organic Chemistry
Employee degree:

BS, Montana State University

PHD, North Dakota State University

  • Professor 2018-present
  • Associate Professor, Ohio Northern University, Ada, OH, 2012-2018
  • Assistant Professor, Ohio Northern University, Ada, OH, 2006-2012
  • Research/Teaching Assistant, North Dakota State University, Fargo, ND 2001-2006


  • B.S., Chemistry, Montana State University-Billings, Billings, MT, 2001
  • Ph.D., North Dakota State University, 2006

Teaching Interests

  • Organic Chemistry
  • Organic Synthesis
  • Medicinal Chemistry

Research Interests

  • New catalyst/ligand design for asymmetric organic processes
  • Stereoselective tin-free radical reactions

Selected Publications

  • Wijesooriya, C. S.; Smith, E. A.; Nieszala, M.*; Stafford, A.*; Zimmerman, J. R. Coumarin-based Fluorescent Probes for Selectively Targeting and Imaging the Endoplasmic Reticulum in Mammalian Cells. Photochem. and photobio. 2018, ASAP.
  • Zimmerman, J. R.; Criss, C.*; Evans, S.*; Ernst, M.*; Nieszala, M.*; Stafford, A.*; Szczerba, J.* Fluorescent sensor for fluoride anion based on a sulfonamido-chromone scaffold. Tet. Lett. 2018, 59, 2473-2476.
  • Zimmerman, J. R. Fluorescent compounds as sensing agents. U.S. Patent 20,170,241,969, 2017.
  • Zimmerman, J. R.; Johntony, O.;* Steigerwald, D.;* Criss, C.;* Myers, B. J.; Kinder, D. H. The Synthesis of a New Class of Highly Fluorescent Chromones via an Inverse-Demand Hetero-Diels–Alder Reaction. Org. Lett. 2015, 17, 3256–3259.
  • Zimmerman, J. R.; Myers, B. J.; Bouhall, S.;* McCarthy, A.;* Johntony, O.;* Manpadi, M. A two-step, single pot procedure for the synthesis of substituted dihydropyrazolopyrimidines. Tetrahedron Lett. 2014, 55, 936–940.
  • McCarthy, A.;* Spatney, R.;* Manpadi, M.; Myers, B. J. Zimmerman, J. R. A direct conversion of carboxylic acids to methylthiomethyl esters using a microwave-assisted pummerer rearrangement with dimethylsulfoxide. Tetrahedron Lett. 201253, 4782–4784.
  • Zimmerman, J. R.; Manpadi, M.; Spatney, R. Tin-free Radical Reactions Under Minimal Solvent Conditions for the Synthesis of Substituted Chromones and CoumarinsGreen Chem201113, 3103-3106.
  • Zimmerman, J. R.; Manpadi, M.; Spatney, R.; Baker, A. Diastereoselective Tin-Free Tandem Radical Additions to 3-Formylchromones. J. Org. Chem. 201176, 8076–8081.
  • "Handbook of Cyclization Reactions; CH. 23: Radical Cyclizations." Sibi, M. P.; Zimmerman, J.; Holloway, A. Wiley-VCH, 2009.
  • Sibi, M. P.; Zimmerman, J. Pyrones to Pyrans: Enantioselective Radical Additions to Acyloxy Pyrones. J. Am. Chem. Soc. 2006128, 13346-13347.
  • Lee, S.; Lim, C. J.; Kim, S.; Subramanyam, R.; Zimmerman, J.; Sibi, M. P. Enantioselective Conjugate Radical Addition to a'-Hydroxy Enones. Org. Lett. 20068, 4311-4313.
  • Sibi, M. P.; Petrovic, G.; Zimmerman, J. Enantioselective Addition/Trapping Reactions with a,b-Disubstituted Enoates. Synthesis of anti-Propionate Aldols. J. Am. Chem. Soc. 2005127, 2390-2391.
  • Sibi, M. P.; Hultin, P. G.; Hein, J. E.; Zimmerman, J. Stereoselective Radical Conjugate Additions: Application of a Fluorous Oxazolidinone Chiral Auxiliary for Efficient tin Removal. Org. Lett. 20057, 2755-2758.
  • Sibi, M. P.; Manyem, S.; Zimmerman, J. Enantioselective Radical Processes Chem. Rev. 2003, 103, 3263-3295.
  • Sibi, M. P.; Zimmerman, J.; Rheault, T. Enantioselective Conjugate Radical Addition to b-Acyloxy Acrylate Acceptors: An Approach to Acetate Aldol-Type Products Angew. Chem. Int. Ed. 2003, 42, 4521-4523.