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Research Accomplishments/Published Chemistry Research


While it is a significant professional accomplishment for chemistry and biochemistry majors to engage in mentored research throughout the school year and during extensive summer research experiences, it is a major accomplishment to produce externally peer-reviewed scholarship (i.e. journal articles, patents, or book chapters). Our accomplished professors and students make significant contributions that advance the body of knowledge in the chemistry and biochemistry fields. Check out the following list of research completed at ONU that has been recently published. (ONU faculty members are in bold, and ONU student co-authors are indicated with a *.)

Donald J. Bettinger Department of Chemistry and Biochemistry Recent Faculty Publications

Graziano, B. J.*; Collins, E. M.*; McCutcheon, N. M.*; Griffith, C. L.*; Braunscheidel, N. M.*; Perrine, T. M.; Wile, B. M. Palladium complexes bearing κ²-N,N and κ³-N,N,O pendant amine bis(phenolate) ligands. Inorg. Chim. Acta. 2019, 484, 185-196.
Wijesooriya, C. S.; Smith, E. A.; Nieszala, M.*; Stafford, A.*; Zimmerman, J. R.Coumarin-based Fluorescent Probes for Selectively Targeting and Imaging the Endoplasmic Reticulum in Mammalian Cells. Photochem. and photobio. 2018, ASAP.
Lavoie, M.; Gali, M.; Maps, F.; Levasseur, M.; Sevigny, C.; Kieber, D. J.; Sunda, W. G.; Spiese, C. E. Modelling dimethylsulfide diffusion in the algal external boundary layer: implications for mutualistic and signaling roles. Environ. Microbiol. 2018, 20, 4157-4169.
Spiese, C. E. Determination of the diffusion constants of dimethylsulfide and dimethylsulfoniopropionate by diffusion-ordered nuclear magnetic resonance spectroscopy. Marine Chem. 2018, 207, 77-83.
Celius, T. C.; Peterson, R. C.; Anderson-Wile, A. M.; Kraweic-Thayer, M.* From Observation to Prediction to Application: A Guided Exercise for Liquid-Liquid Extraction. J. Chem. Ed. 2018, 95, 1626-1630.
Zimmerman, J. R.; Criss, C.*; Evans, S.*; Ernst, M.*; Nieszala, M.*; Stafford, A.*; Szczerba, J.* Fluorescent sensor for fluoride anion based on a sulfonamido-chromone scaffold. Tet. Lett. 2018, 59, 2473-2476.
Wile, B. M. Chemistry: The Science in Context, 5th Ed. - Student Solutions Manual; W.W. Norton & Co.: New York, 2018 705 pages. ISBN: 978-0-393-60381-1
Wile, B. M. Chemistry: The Science in Context, 5th Ed. - Instructor Solutions Manual; Volume 2: Chapters 12-22; W.W. Norton & Co.: New York, 2018 624 pages. ISBN: 978-0-393-61725-2
Wile, B. M. Chemistry: The Science in Context, 5th Ed. - Instructor Solutions Manual; Volume 1: Chapters 1-11; W.W. Norton & Co.: New York, 2018 885 pages. ISBN: 978-0-393-60383-5
Dunn, Z. L.*; Hammer, M. A.*; Topham, B. J.; Perrine, T. M. Linker Effects in Porphyrin Polymeric Donor Materials for Photovoltaic Devices. J. Phys. Chem. C 2017, 121, 12018-12024.
Zimmerman, J. R. Fluorescent compounds as sensing agents. U.S. Patent 20, 170, 241, 969, Feb. 23, 2017.
Wile, B. M. Crystal structure of {N-[(6-bromopyridin-2-yl)-(phenyl)methylidene]-2, 6-dimethylaniline-K2N, N’}dichloridozinc dichloromethane hemisolvate. Acta Cryst. 2017, E73(Pt 7), 932-935.
Spiese, C. E. , Sanford, J. L., Bowling, M. N.*; Tatarkov, E. T.*; Pinkney, A. L. Methanesulfonate supports growth as the sole sulfur source for the marine diatom Thalassiosira pseudonana NCMA 1335. Aquat. Micro. Ecol., 2017, 78, 177-185.
Hrometz, S. L.; Ebert, J. A.*; Grice, K. E.*; Nowinski, S. M.; Mills, E. M.; Myers, B. J. ; Sprague, J. E. Potentiation of 3, 4-methylenedioxymethamphetamine (MDMA)- induced hyperthermia and FAT/CD36 expression in chronically exercised animals. Temperature 2016, 3, 1-10.
Bowser, A. K.*; Anderson-Wile, A. M. ; Johnston, D. H.; Wile, B. M. Diamine bis(phenolate) and pendant amine bis(phenolate) ligands: Catalytic activity for the room temperature Pd-catalyzed Suzuki-Miyaura coupling reaction. Appl. Organomet. Chem. 2016, 30, 32-39.
Spiese, C.; Le, T.*; Zimmer, R. L.*; Kieber, D. J. Dimethylsulfide membrane permeability, cellular concentrations and implications for physiological functions in marine algae. J. Plankton Res. 2016, 38, 41-54.
Anderson-Wile, A. M. Introducing 2D NMR Spectroscopy to Second-Year Undergraduate Chemistry Majors using a Building-Up Approach. J. Chem. Educ. 2016, 93, 699-703.
Rauckhorst A. J.; Pfeiffer, D. R.; Broekemeier K. M. The iPLA2γ is identified as the membrane potential sensitive phospholipase in liver mitochondria. FEBS Letters 2015, 589, 2367-2371.
Motz, V. A.; Bowers, C. P. ; Kneubehl, A. R.*; Lendrum, E. C.*; Young, L. M.; Kinder, D. H. Efficacy of the saponin component of Impatiens capensisMeerb. in preventing urushiol-induced contact dermatitis. J. Ethnopharmacology 2015, 162, 163-167.
Kasting, B. J.*; Bowser, A. K.*; Anderson-Wile, A. M. ; Wile, B. M. Synthesis and Metallation of a Ligand: An Interdisciplinary Laboratory Experiment for Second-Year Organic and Introductory Inorganic Students. J. Chem. Educ. 2015, 92, 1103-1109.
Zimmerman, J. R. ; Johntony, O.*; Steigerwald, D.*; Criss, C.*; Myers, B. J. ; Kinder, D. H. The Synthesis of a New Class of Highly Fluorescent Chromones via an Inverse-Demand Hetero-Diels–Alder Reaction. Org. Lett. 2015, 17, 3256-3259.
Perrine, T. M.; et. al. Advances in molecular quantum chemistry contained in the Q-Chem 4 program package. Molecular Physics 2015, 113, 184-215.
Zimmerman, J. R. ; Myers, B. J. ; Bouhall, S.*; McCarthy, A.*; Johntony, O.;* Manpadi, M. A two-step, single pot procedure for the synthesis of substituted dihydropyrazolo­pyrimidines. Tetrahedron Lett. 2014, 55, 936-940.
Wile, B. M. ; Brewer, K. S. Chemistry: The Science in Context, 4th Ed. - Student Solutions Manual; W.W. Norton & Co.: New York, 2014 648 pages. ISBN: 978-0-393-93647-6
Wile, B. M. ; Brewer, K. S. Chemistry: The Science in Context, 4th Ed. - Instructor Solutions Manual; Volume 2: Chapters 12-22; W.W. Norton & Co.: New York, 2014 607 pages. ISBN: 978-0-393-93722-0
Wile, B. M. ; Brewer, K. S. Chemistry: The Science in Context, 4th Ed. - Instructor Solutions Manual; Volume 1: Chapters 1-11; W.W. Norton & Co.: New York, 2014 763 pages. ISBN: 978-0-393-93721-3
Spiese, C. ; Tatarkov, E. A.* Dimethylsulfoxide reduction activity is linked to nutrient stress in Thalassiosira pseudonanaNCMA 1335. Mar. Ecol. Prog. Ser. 2014, 507, 31-38.
Dickson-Karn, N. M. ; Olson, C. M.*; Leu, W. C. W.; Hartley, C. S. Intramolecular charge transfer in donor-bridge-acceptor compounds with paired linearly conjugated or cross-conjugated pathways. J. Phys. Org. Chem. 2014, 27, 661-669.
Broekemeier, K. M. ; Rauckhorst, A. J.; Pfeiffer, D. R. Activation/Deactivation of the Ca 2+ -independent Phospholipase A 2 (iPLA 2 ) in Rat Liver Mitochondria by Changes in the Energetic State. J. Lipid Res. 2014 , 55 , 826-836.
Williams, D. R.; Myers, B. J. ; Mi, L.; Binder, R. J. Studies for the Total Synthesis of Amphidinolide P. J. Org. Chem. 2013, 78, 4762-4778.
Fenlon, E.; Myers, B. J. Profiles in Chemistry: A Historical Perspective on the National Organic Symposium. J. Org. Chem. 2013, 78, 5817-5831.
Auriemma, F.; De Rosa, C.; Di Girolamo, R.; Silvestre, A.; Anderson-Wile, A. M. ; Coates, G. W. Small Angle X-ray Scattering Investigation of Norbornene-Terminated Syndiotactic Polypropylene and Corresponding Comb-Like Poly(macromonomer). J. Phys. Chem. B 2013, 117, 10320-10333.
Motz, V. A.; Bowers, C. P. ; Young, L. M.; Kinder, D. H. The Effectiveness of Jewelweed, Impatiens capensis, the Related Cultivar I. balsamina and the Component, Lawsone in Preventing Post Poison Ivy Exposure Contact Dermatitis. J. Ethnopharmacology 2012, 143, 314-318.
McCarthy, A.*; Spatney, R.*; Manpadi, M.; Myers, B. J. ; Zimmerman, J. R. A direct conversion of carboxylic acids to methylthiomethyl esters using a microwave-assisted pummerer rearrangement with dimethylsulfoxide. Tetrahedron Lett. 2012, 53, 4782-4784.
Joshi, S. R.; Sarpong, Y. C.; Peterson, R. C. ; Scovell, W. M. Nucleosome Dynamics: HMGB1 Relaxes Canonical Nucleosome Structure to Facilitate Estrogen Receptor Binding. Nucleic Acids Res. 2012, 40, 10161-10171.
Anderson-Wile, A. M. ; Edson, J. B.; Coates, G. W. Living Transition Metal Catalyzed Alkene Polymerization: Polyolefin Synthesis and New Polymer Architectures. In Polymer Science: A Comprehensive Review; Matyjaszewski, K.; Möller, M., Coates, G., Sawamoto, M., Eds.; Elsevier B. V.: The Netherlands 2012 pp 739-778.
Anderson-Wile, A. M. ; Auriemma, F.; De Rosa, C.; Silvestre, A.; Coates, G. W. Ring- Opening Metathesis Polymerization of Norbornene-Terminated Syndiotactic Polypropylene. Macromolecules 2012, 45, 7863-7877.
Anderson-Wile, A. M. ; Wile, B. M. ; Wen, Q.; Shen, H. Corrosion at the Polymer- Metal Interface in Artificial Seawater Solutions. Int. J. of Corrosion 2012 , Article ID 496960.
Ruiz-Orta, C.; Fernandez-Blazquez, J. P.; Anderson-Wile, A. M. ; Coates, G. W.; Ruff, C.; Alamo, R. G. Isotactic Polypropylene with (3, 1) Chain-Walking Defects: Characterization, Crystallization and Melting Behaviors. Macromolecules 2011, 44, 3436-3451.
Evans, A. S.; Cohen, A. D.; Gurard-Levin, Z. A.; Kebede, N.; Celius, T. C. ; Miceli, A. P.; Toscano, J.P. Photogeneration and Reactivity of Acyl Nitroso Compounds. Can. J. Chem. 2011, 89, 130-138.
Zimmerman, J. R. ; Manpadi, M.; Spatney, R.*; Baker, A.* Diastereoselective Tin-Free Tandem Radical Additions to 3-Formylchromones. J. Org. Chem. 2011, 76, 8076-8081.
Zimmerman, J. R. ; Manpadi, M.; Spatney, R.* Tin-free Radical Reactions Under Minimal Solvent Conditions for the Synthesis of Substituted Chromones and Coumarins. Green Chem. 2011, 13, 3103-3106.
Anderson-Wile, A. M. ; Edson, J. B.; Coates, G. W. Living Olefin Polymerization for Polyolefin Architectures. In Complex Macromolecular Architectures: Synthesis, Characterization, and Self-Assembly; Hadjichristidis, N., Hirao, A., Tezuka, Y., Du Prez, F., Eds.; Wiley-VCH: Germany, 2011 pp 267-316.
Murthy, S. N.; Sammeta, S. M.; Bowers, C. P. Magnetophoresis for enhancing transdermal drug delivery: Mechanistic studies and patch design. J. Controlled Release 2010, 148, 197-203.
Perrine, T. M. ; Dunietz, B. D. Contact geometry symmetry dependence of field effect gating in single molecule transistors. J. Amer. Chem. Soc. 2010, 132, 2914.
Celius, T. C. Fast Hetero-Diels-Alder Reactions Using 4-Phenyl-1, 2, 4-triazoline-3, 5-dione (PTAD) as the Dienophile. J. Chem. Educ. 2010, 87, 1236-1237.
Department of Chemistry and Biochemistry

Lori Kindle

419-772-2336
l-kindle@onu.edu
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