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Medicinal Chemistry Seminar to Deal with Cancer Treatment

Dec 2, 2008
Ohio Northern University will host a medicinal chemistry seminar Dec. 3 at 6 p.m. in the Meyer Hall of Science's annex room 105.

Tara Rheault, Ph.D., an oncology medical chemistry researcher with GlaxoSmithKline at Research Triangle Park in North Carolina, will be the speaker. Her topic is "Potent and Selective Inhibitors of Polo-Like Kinase (PLK1): Novel Anti-mitotic Agents for the Treatment of Cancer."

Lack of proper cell cycle control is a hallmark of cancer cells. Interruption of the cell cycle through the use of drugs such as Taxol is an effective approach to cancer therapy. PLK1 (Polo-like kinase 1) has been shown to play an integral role in the progression of cells, particularly rapidly dividing cancer cells. The presentation will deal with recent research to develop IV-administered therapies based on PKL1.

The presentation, designed for chemistry, biology and pharmacy students and faculty, is free and open to the public.
To learn more, contact Jake Zimmerman, Ph.D., assistant professor of chemistry and biochemistry, at 419-772-2342.

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