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Kimberly Broekemeier

Associate Professor of Chemistry
Department of Chemistry and Biochemistry
Meyer 270
525 S. Main Street
Ada, OH 45810
(419) 772-2339
Professional Experience: 
  • 2000 - present Associate Professor, Department of Chemistry and Biochemistry, Ohio Northern University, Ada OH
  • 1998 - 2000 Assistant Professor of Chemistry, Department of Chemistry and Biochemistry, Ohio Northern University, Ada, OH
  • 1996 - 1998 Senior Research Scientist, The Department of Medical Biochemistry, Ohio State University, Columbus, Ohio
  • 1992 - 1996 Research Associate, The Department of Medical Biochemistry, Ohio State University, Columbus, Ohio.
Education: 
  • B.A. 1977-1981, St. Olaf College, Northfield, MN., Magna Cum Lauda (Chemistry)
  • Ph.D. 1984-1990, University of Minnesota, Minneapolis, MN. (Biochemistry), Thesis title: "Mechanism of the Inner Membrane Permeability Transition in Rat Liver Mitochondria"  Advisor:  Dr. M.E. Dempsey.
  • Postdoctoral 1990-1992, Hormel Institute, University of Minnesota, Austin, MN. Advisor:  Dr. Douglas R. Pfeiffer
Teaching Interests: 
  • Introductory Chemistry
  • Introductory Biochemistry
  • Advanced Biochemistry
Research Interests: 
  • Mitochondrial permeability regulation
  • Phospholipase activity
  • Mitochondrial autophagy
Selected Publications: 

1.   Kimberly M. Broekemeier, Martha E.Gadd, Elliott D. Crouser, Jatendra Kumar, Gustav Graff, Douglas R. Pfeiffer  “Mitochondrial iPLA2 Activity Modulates the Release of Cytochrome c from Mitochondria and Influences the Permeability Transition”  (2006)  J.Biol.Chem.  281:6931-9

2.   Elliott D. Crouser, Martha E Gadd, Mark W. Julian, Jennifer E. Huff, Kimberly M. Broekemeier, Karen A. Robbins, and Douglas R. Pfeiffer  “Quantitation of Cytochrome c Release from Rat Liver Mitochondria.”  (2003)  Anal. Biochem.  317:67-75.

3. K.M. Broekemeier, J.R.Iben, E. G. LeVan, E. D. Crouser and D.R. Pfeiffer. “Pore Formation and Uncoupling Initiate a Ca2+-Independent Degradation of Mitochondrial Phospholipids."  (2002) Biochemistry 41:7771-7780.

4. K. M. Broekemeier, C. K. Klocek, and D. R. Pfeiffer: "Proton Selective Substate of the Mitochondrial Permeability Transition Pore: Regulation by the Redox State of the Electron Transport Chain." (1998) Biochemistry 37. 13059-13065.

5. K. M. Broekemeier and D. R. Pfeiffer: “Inhibition of the Mitochondrial Permeability Transition by Cyclosporin A During Long Time Frame Experiments:  a relationship between pore opening and the activity of mitochondrial phospholipases.” (1995) Biochemistry 34, 16440-16449.

6. P. Bernardi, K. M. Broekemeier and D. R. Pfeiffer: Invited Review.  "Recent Progress on Regulation of the Mitochondrial Permeability Transition; A Cyclosporin Sensitive Pore in the Inner Mitochondrial Membrane" (1994) J. Bioenerg. Biomembr. 26, 509-517.

7. K. M. Broekemeier, R. J. Krebsbach and D. R. Pfeiffer: "Inhibition of the Mitochondrial Ca2+ Uniporter by Pure and Impure Ruthenium Red." (1994) Molecular and Cellular Biochem. 139, 33-40.