Kimberly Broekemeier | Ohio Northern University

Biography:

Professional Experience:

2000 - present Associate Professor, Department of Chemistry and Biochemistry, Ohio Northern University, Ada OH
1998 - 2000 Assistant Professor of Chemistry, Department of Chemistry and Biochemistry, Ohio Northern University, Ada, OH
1996 - 1998 Senior Research Scientist, The Department of Medical Biochemistry, Ohio State University, Columbus, Ohio
1992 - 1996 Research Associate, The Department of Medical Biochemistry, Ohio State University, Columbus, Ohio.

Education:

B.A. 1977-1981, St. Olaf College, Northfield, MN., Magna Cum Lauda (Chemistry)
Ph.D. 1984-1990, University of Minnesota, Minneapolis, MN. (Biochemistry), Thesis title: "Mechanism of the Inner Membrane Permeability Transition in Rat Liver Mitochondria" Advisor: Dr. M.E. Dempsey.
Postdoctoral 1990-1992, Hormel Institute, University of Minnesota, Austin, MN. Advisor: Dr. Douglas R. Pfeiffer

Teaching Interests:

Introductory Chemistry
Introductory Biochemistry
Advanced Biochemistry

Awards:

Research Interests:

Mitochondrial permeability regulation
Phospholipase activity
Mitochondrial autophagy

Selected Publications:

1. Kimberly M. Broekemeier, Martha E.Gadd, Elliott D. Crouser, Jatendra Kumar, Gustav Graff, Douglas R. Pfeiffer “Mitochondrial iPLA₂ Activity Modulates the Release of Cytochrome c from Mitochondria and Influences the Permeability Transition” (2006) J.Biol.Chem. 281:6931-9

2. Elliott D. Crouser, Martha E Gadd, Mark W. Julian, Jennifer E. Huff, Kimberly M. Broekemeier, Karen A. Robbins, and Douglas R. Pfeiffer “Quantitation of Cytochrome c Release from Rat Liver Mitochondria.” (2003) Anal. Biochem. 317:67-75.

3. K.M. Broekemeier, J.R.Iben, E. G. LeVan, E. D. Crouser and D.R. Pfeiffer. “Pore Formation and Uncoupling Initiate a Ca²⁺-Independent Degradation of Mitochondrial Phospholipids." (2002) Biochemistry 41:7771-7780.

4. K. M. Broekemeier, C. K. Klocek, and D. R. Pfeiffer: "Proton Selective Substate of the Mitochondrial Permeability Transition Pore: Regulation by the Redox State of the Electron Transport Chain." (1998) Biochemistry 37. 13059-13065.

5. K. M. Broekemeier and D. R. Pfeiffer: “Inhibition of the Mitochondrial Permeability Transition by Cyclosporin A During Long Time Frame Experiments: a relationship between pore opening and the activity of mitochondrial phospholipases.” (1995) Biochemistry 34, 16440-16449.

6. P. Bernardi, K. M. Broekemeier and D. R. Pfeiffer: Invited Review. "Recent Progress on Regulation of the Mitochondrial Permeability Transition; A Cyclosporin Sensitive Pore in the Inner Mitochondrial Membrane" (1994) J. Bioenerg. Biomembr. 26, 509-517.

7. K. M. Broekemeier, R. J. Krebsbach and D. R. Pfeiffer: "Inhibition of the Mitochondrial Ca²⁺ Uniporter by Pure and Impure Ruthenium Red." (1994) Molecular and Cellular Biochem. 139, 33-40.